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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d28210cc7bed191b3cfd1ebcde046201c6602b18d55409bf716f2d6544ff974' 
  AND token = 'z2iVHsngoVHtsY/kl7+yFdS+5Queepam1jlmes1maRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}