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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '215e515316dc6f4495ad3ee5aee939dc3c8372fc06037025f7c07d98e66a7299' 
  AND token = 'XTdEEtVhobWZ/qymMSdQgJXWARZSU86tVWFXAxFaM/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}