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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b507cce49578841725f2452f125833f4d2994ba53bb18fd7f5f6fe4518428e2' 
  AND token = 'i3SG2Mq8QhZ/+Z04ZHMoQFhzBv9iWYRrnUaD13Y1avQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}