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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca569dda18140d2946391193fb44f0f2fb16e22eaa6e953a7fd7af4cff6b3d01' 
  AND token = 'SbHVilJiM4cr34b2pZXleBQQG4hS8GAbsxpaC9oDNeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}