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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2583b038469540c45bd1dd01c02bcda5ef9b0c8e995787b663967f0b90a937b3' 
  AND token = 'jWQN3NBWAXc606EkzkpPpqbybwoC20N6Y4HzrOoOrOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}