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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a77fd18373fe9c7ee543c5042a76e3dc2d89f7ab6886a1b0b7a811b591c5043a' 
  AND token = 'kMGoifhcZ+ozhKaBdpj+84O2IOH2FWR4rxIpacoabG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}