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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70db3a29a89239994649af5a1a614c10a61725b1b459d4e68571a03f40a76d6b' 
  AND token = 'F3p6hYtrlvhgLZV8XA3nZFpkYrCu26erWdGaGlEPqeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}