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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '464e23d43431e02846a8b183d5fc7374ea9803559ff716082e5a9a15fa7b1861' 
  AND token = '/nbJVzcALB92yLxct+HBewYytA0fCs6+w421F0czSRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}