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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab73ef2e279e982bde35f83ec2977fffffd65d50847816af2f39802a2f9e1f9' 
  AND token = 'MzmiFVA5oqVHJHn91LSPv0vfl4Xuh+Vweolsiud8QA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}