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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdef410577ef170fa29e98545f72b66c7a38dcf516cd63f1a5ab571e27deaaf0' 
  AND token = 'f4xes3hIjetpyGcjtIun4NTc2CY3Ejb1vtiiKGnKgFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}