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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cd645b256d0168fc2f95577caf71ed0ab347d11be31cb86eef584c1b62d2cbf' 
  AND token = 'XEzpR3AsEzQRZFJjtOcjrrN0B7P4UzgbKtzOnz1LKoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}