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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa7743b235f39d560d5920ab5de2b7b4f62c316c76adb1116f59796db4e21a22' 
  AND token = 'BsYK6y3lvqAGPSMr/EGV/1dKIX6u9voDV4iYPoFy3gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}