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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2295137351bbe4f62950eac699e847db232ccd8afe51a52f8fb56b4ec868200' 
  AND token = 'rlPGjS5z50oCtCVBiZlfRHs9Y0DL+DxSHwbpldL+UF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}