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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b3bb00832aa61049867c94d5f8352c9d02bc32c7f58c0b2134e583121c974fa' 
  AND token = 'EccW/Q8DywAzdGk/WPo6MoJHaG8lrHOjYQy9lS7F4V8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}