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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6a11916b075c47138687a28eb947d35013d0b42f1e243e72e69d98f5152fe2c' 
  AND token = 'fX8VRuKz3i05FpK1CIAb55g+V2bTNDR8pTc0vScFdQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}