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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2fd6aaa8d0e516d0cd26a25484e8a859f8931f655156d9687214b382c2a926' 
  AND token = 'bqJl88YUrWT2GiQCOYtJmepTg5bMXzGH8zvK5GB8rj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}