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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43dcf62a31b1136c9bea0a0fa599b92d1603a5fca31b1bad721138eb4cf47c3f' 
  AND token = 'Q4QzxowYpluiEz9XD1j/cSn7brxP2IAhodxRYKKnz+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}