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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ec1ca1d61e12f69e6a6112ac0d6ccdaac7606bac11663f15c0329146b56f2ef' 
  AND token = 'vxIy5Collop/E/EPE4uHDxk0+n+Ngh9+ShC8W+qs1+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}