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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fc6f03b45a535a0b7e003933451e3c1b170e7f04d08e23e20adb0103c695fe2' 
  AND token = 'hYPjn4YEB3X8LmN0PA8wbSAeCSrK5b7JZlvdBD2vBrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}