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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db0b5b9a6bc41dbf3ea99888f912bef800091d04385ffe12f8efb2736339239a' 
  AND token = 'ASu3Y6LqMStlyJPw2PcsvuuGm3ow4zX+ssV8Xs6uTX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}