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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6a13f70a76bfd06211947a619d9cef585af9e5eaf78868d3bfdd0fa7c0f6b5' 
  AND token = '6IFtsRHZ/RZi0C2brGiNFrCABl7dxHi2d5RZmUl2uCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}