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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81573ee8ce0762da79c95fe818f517db15085255e591a6b20b723e3d577c0936' 
  AND token = 'ICoz6DHhUMb94eUzK/8r7Gfpss8SVAWhSrrO8UNpyi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}