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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd090e34d1b9091cdd1be2f0e1280ac55f326d1b41c54ce57c8ba3d68f25f7a' 
  AND token = '4zBDZCtfjdYX9lFfi60i2jJKTZtQ7xfW29GQ9Kagp10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}