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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5752e40ce1bf10cb81fdca48aff5a9e081b3c406e8b10f3a2c32cbe777110f90' 
  AND token = 'YMk7elFPiZnCo450L2SkFGdTCImFuJBS6UMbdYnQ7OY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}