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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '108318882ed655d3be79bac15197e0c1f48b4a718e990a645a60d2e9bc53b9f6' 
  AND token = 'ctAMblDrxZcUUFHbNK4NGXaUBBlkWaHLMlxv5fjaFkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}