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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4922e000e3b494ff1723d44876dd784108030f2d415183b8fce6de25e1b799f1' 
  AND token = 'V2l6dQt+OMCZosoTz/hcJaUHyaLZeMS3kvscy6xbG2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}