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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e134884cd2070dfd3c065cf0db461148765554ecaad3b4d1bd8cbe892731b382' 
  AND token = 'gp6EQFLsF+Loyy/Usndb4tNfK7ln61lkUy0TJSHQ1ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}