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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372666c48c7090d7e1122c0814d696b90e1e941396e1d96d34b6f3a17662b242' 
  AND token = 'eURhQA6OBon21UhsSVLJyuyjURFezz7WMrdS19Gymf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}