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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8a378f1fb4458ea6dbe1f7a1bc762308ea0ab13d5ef31752fb6a79915e0c41c' 
  AND token = '8QqBEnGnBbRC27k26JpgW/4XM6dTLYbdI82duoQD0Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}