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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5545890857d0bc7ff208484901c14b0f1b8ddb434a657e8ec9a146558d60979c' 
  AND token = 'ENA25iAOFbK7LM6B1q+H3IPsExFAQJ7igTobg+D/lhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}