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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '846cdb4b70456f64bfcc4e86481922a0dedf510f386a94c7509969d96799aee8' 
  AND token = 'DV+OoVbKzVa3hB6c809/n0/TV3GZO24k+jv6hVf5J1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}