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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11146c13519a6450560ffb3f21c1c47b76c339cb08d1f74eb238581cdafa761b' 
  AND token = 'jmpds0uMJqcr0A3rJpvERKSmmWo9/N1YGX6TNy1VMmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}