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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07cd952252f9732b212b3de0b9c71a3aed7d78125d7458567c3c2fabfadd09d1' 
  AND token = 'qnXDoGvNw8DkuPBWxARMSzD/4O9Nyl16FXKDymPd3is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}