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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ff8708787a34a7256f8e8142a083a9e7f0eb39c3b162b67ade0d8405f62cd22' 
  AND token = 'd5fB0ooq/xblCJslZa8KHUzMaFE9WrKkLBxyA24mbLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}