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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8c9c924efe54aa43326995590963ffe280bda5e32fb62223f1331bc42cd24c1' 
  AND token = 'WN7uHrfR+JR+Uz9ItP7WL5Sa92KgXSW0fHMtOv1I+xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}