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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '127ee6c0ebba0e1215bf44928021e405ee68c4cab75fb61fdb69e426dd78854b' 
  AND token = 'GMibO1W1Z5mHyuyX9UScqK7dSiVz15/mQyPF9Q0SaJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}