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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87e56c293ffe487cd2047e4d8d0a1a6bd83244957266bb2f11e0b23a14ca8a44' 
  AND token = 'Drk12ohLtf5YQM9QPvn5mCW8BRkSJaBpHkMiIiCdSAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}