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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cae42c26a1618cc561744456969e954e69fc005393e20876214c47c1df677809' 
  AND token = 'JVDUMYvl4X00Mj+skNZ/0ZIaTKgfUyKrl5Xhn51lgtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}