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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ebda91db4191d60fefba2b5cd728a7748b4a91938972fad29584b0afe8bc9e' 
  AND token = 'EUmM7chx+WehxgOCmaKk990HSgj2rosM/CVpEjJAQo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}