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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344725edc46eb40d0c292ccfd4de526432c7d95988980211ed807f45f4307fee' 
  AND token = 'b3xXY93/7i3HdbJR8WTOg+RNOKV/kAUyHuiwFSCE6KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}