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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bfdb3c6f225693e877677141260f5d2ee1e2905ed787806b868772ee6a68024' 
  AND token = 'uO+jKJnbi1IukA+1mZtQ9opXxK2FY40/cQ2HrIGFUw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}