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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f490f71e85571e4bc42c7c0873b0e90ed17ab52dfecf1d1e872730ddb6afbe9f' 
  AND token = 'EqnLLf7ks+BGJP/+usFbm0qLBnS5L6lZxvZNtRWXteo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}