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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79dc9e5ac52992e8dbf3841e76c51485675e09560fd702f6e948a1be453f0256' 
  AND token = 'kPCRdw5GyHivGvxDkn69lBidwvvHJF3ZasLe0XCPTvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}