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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4347ed5022ece308a1835fe3b19e5df4dba27daf1f5d9eefc30e5bcb67a0610' 
  AND token = 'k1wN4phe4USusq3B29tVyeKzby1i8O2b7iK4M3/TbKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}