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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cd6b52cf013d790adf3618c0f5b86d07e0d9c4baf559471d744a051d04c5d70' 
  AND token = 'mlQEbaLUk6x0h9imtXz1z+uPsRVMcm5JBmdRmZnXdFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}