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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '131ec761f0290fdeccbc6f3f44e7601068797cd02728691e1e4c8d56979d4c2b' 
  AND token = 'IGb/k5CkVa0RgBZ0tr0wh3K1FqHL26WHR9/C5WfHb1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}