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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac65c27c9a595fea969f51d7c90b3e8dc946dd82652c46411926d8ec68887058' 
  AND token = 'O6a2oYmfAn2Lm9aC1LW1Ps8EOcIaARWhLMd/VmevhP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}