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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b89d88bd6714d4aea1b289d92988a9403b988c0e2ae9d38f01d5a4e8f07d2341' 
  AND token = 'I2YH41g+gYRozjoiOOie28PNh2FarRNlgg/0TvFN+5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}