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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595e361f5d9b07af4bd5721473b9b91bcffb485acf4d28995ef01b567ffc93ff' 
  AND token = 'ekRfF0YCi5YKYuyph7UXJVJ7n6dvCZzyTZIC1r/Gkno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}