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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287656b173b777b61d8eef7e1e74c8d26d7bb0a97bf1086ab66c6c6491201849' 
  AND token = '0MZF7ETK2DvfJux3U26E/jkzejBcHo+E3i52L4fLNUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}